From Dentistry IQ June 29, 2011
Journal of Oral Implantology — The health of the surrounding tissue affects the success of a dental implant . Identifying and reducing risk factors is therefore a key step in the implant process. Now a combination of genes has been identified as a possible indicator of greater tissue destruction, leading to negative outcomes for implants .
The authors of an article in the current issue of the Journal of Oral Implantology report on a study of individuals with the combination of interleukin (IL)-1 allele 2 at IL-1A -889 and IL-1B+3954 . These people are “genotype positive” and are susceptible to increased periodontal tissue destruction.
Peri-implantitis , or the process of tissue inflammation and destruction around failing implants, is very similar to periodontal disease . The researchers sought to find any association of these genotypes with the severity of peri-implantitis progression and the effect of this combination on treatment outcomes.
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