Oral Health Group

Oragenics – Innovative Biopharmaceuticals from Oral Science


A long time ago in a galaxy far, far away, I had the opportunity to go to graduate school at the Harvard/Forsyth Dental Center. It is the research home to many brilliant minds in dentistry, mine unfortunately was not one of them. Surprisingly, they were some of the most approachable and interesting individuals I have ever met. Dr. Jeff Hillman was one of them.

Dr. Jeffery Hillman began his basic research into the concept of replacement therapy 

Rampant caries.

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for preventing dental caries or cavities in the late 1970s at the Forsyth Institute in Boston. He transferred his research to the University of Florida College of Dentistry in 1992. There, he continued to pursue the development of a genetically engineered strain of Streptococcus mutansthat could help prevent cavities by replacing the body’s natural caries-causing strains of S. mutans

Currently in clinical trials, Oragenics’ patented SMaRT Replacement Therapy™ is a painless, one-time, five-minute treatment that has the potential to offer lifelong protection against tooth decay. Applied topically to the teeth with a swab, the therapy can be administered by dentists in the office or in the field. 


Take a minute and visit www.oragenics.com. It is a fascinating site, and a fascinating example of the future of dental care.

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