Home > Immune Response to Implanted Bone Replacement Graft Materials > Sheikh grafts Fig 1

Sheikh grafts Fig 1

Schematic figure depicting post-implantation events. Immediately after implantation in vivo, a layer of proteins from the microenvironment adsorb and coat the surface of the biomaterial device. This protein adsorption results in attraction, infiltration, and attachment of various cell types such as monocytes, macrophages, and platelets. These cell types release chemokines and cytokines that recruit tissue repair cells to the site of inflammation. These cells produce collagen and result in the fibrous encapsulation of the implanted material. (Adapted from Sheikh and Brooks et al. 2015).14