Keyword
Oral Lesions

December 14, 2020 Feature CancerOral cancerOral HealthPreventive Dentistry

Oral Cancer and the Race Against Time: Use of Psoriasin (S100A7) as a Predictive Marker to Enhance Assessment of Cancer Risk in Oral Lesions

by V. Thorburn, BMSc, MSc, DDS Candidate; C.S. Dong, DMD, BSc (Dent), MSc (Prosthodontics), FRCD(C) and M.R. Darling, BChD, MSc (Dent), MSc (Med), MChD

Introduction Oral squamous cell carcinoma (OSCC) is a potentially debilitating and deadly disease, particularly when diagnosed at an advanced stage.1 Early detection drastically improves prognostic outcomes, making diagnosis a race against time.2 Most cases of OSCC begin as a precursor…

December 11, 2018 Feature Oral HealthProactive Intervention Dentistry

Psoriasin: A New Biomarker in the Identification of Cancer Risk in Oral Lesions

by M.R. Darling, BChd, MSc (Dent), MSc (Med), MChD; A. Hassan, BMedSci (Hons Pathology) Candidate; L. McLean, DDS. Oral and Maxillofacial Surgery Resident

Introduction Approximately 90% or more of oral cancers are squamous cell carcinomas (OSCCs). These often begin as potentially malignant oral lesions such as a white patch (leukoplakia; Fig. 1), or red patch (erythroplakia; Fig. 2), 1 which progress to an…