COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals

Dental care professionals are thought to be at enhanced risk of occupational exposure to SARS-CoV-2, but robust data to support this is lacking. The study “COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals,” published in the Journal of Dental Research (JDR), provides a longitudinal analysis of antibodies to SARS-CoV-2 spike glycoprotein, including early analysis of the impact of vaccination on the immune response.

In June 2020, I,507 West Midlands dental care professionals were recruited to test for baseline seroprevalence, or the proportion of the population that have circulating antibodies to SARS-CoV-2, indicating prior COVID-19 infection. The cohort was followed longitudinally for six months until January/February 2021 through the second wave of the COVID-19 pandemic in the United Kingdom and vaccination commencement.

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