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Key New Molecules Uncovered That Could Help Tackle Tooth Loss And Regeneration

September 3, 2019
by Mrs. Amy King, University of Plymouth


Our teeth take thousands of bites per day, and understanding exactly what holds them in place and how is key to helping people live with their own teeth for longer.

Now new research published in the Journal of Dental Research has shed light on the science behind the formation of the periodontal ligament, which helps keep the tooth stable in the jawbone. This improved understanding will also help scientists work towards regenerating the tissues that support teeth.

The study, led by the Universities of Plymouth and Geneva, shows how a * signaling pathway called Notch, which is known to be activated in stem cells and cancer, is important for periodontal ligament development.

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