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Presence of Oral Bacteria in Cerebral Emboli of Stroke Patients

May 26, 2019
by University of Tampere, ScienceDaily


Researchers at Tampere University have shown for the first time that the cerebral emboli of stroke patients contain DNA from oral pathogens. The research article has been published in the Journal of American Heart Association.

The researchers analysed thrombus aspirates, which neurointerventional radiologists removed from 75 stroke patients as part of emergency treatment. The samples were studied by duplicating bacterial DNA, showing that 79 % of the aspirates contained DNA from bacteria that came from the teeth.

The study is part of a research project at Tampere University, which for ten years has been investigating the effects of bacterial infection in the development of cardiovascular diseases. The research group has previously shown that the same odontogenic bacteria are present in the coronary artery stenoses of patients who have suddenly died, the thrombus aspirates and arterial blood of myocardial infarction patients, ruptured cerebral aneurysms and the thrombus aspirates of patients with lower limb arterial and venous thrombosis.

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