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Mechanism Linking Gum Disease to Heart Disease, Other Inflammatory Conditions Discovered

November 9, 2020
by University of Toronto

U of T Dentistry researchers find first evidence that neutrophil immune cell activity is the missing link connecting periodontal disease with heart disease, cancer, and other inflammatory conditions

The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery. This month, a team of scientists and clinicians led by the University of Toronto’s Faculty of Dentistry say they’ve found the reason why — and it’s related to the body’s own hyperactive immune response. The findings were published in the Journal of Dental Research.

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