Dental Professor Hopes NIH Grant Will Lead To New Therapies For Periodontal Disease

Creighton University School of Dentistry Associate Professor D. Roselyn Cerutis, PhD, has received a grant from the National Institutes of Health (NIH) to study a potential therapy that may help reduce inflammation and bone loss in periodontal (gum) disease.

Cerutis, an associate professor of oral biology, was awarded a three-year $431,348 NIH grant to investigate a molecule in the body called lysophosphatidic acid (LPA). Using a mouse model of periodontal disease, Cerutis will determine whether one of the receptors for lysophosphatidic acid, LPA1, is the primary regulator of both inflammation and bone loss in periodontal disease.

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