Mount Sinai researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and cases when both neurodevelopment conditions are present, which suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Translational Psychiatry in September.
The researchers used baby teeth to reconstruct prenatal and early-life exposures to nutrients and toxic elements in neurotypical children and children with autism, ADHD, or ADHD and autism. They found that each condition has a unique metabolic signature, which shows a combination of dysregulation in metabolic pathways involving essential and toxic elements.
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