Oral Health Group

December 14, 2020 Feature CancerOral cancerOral HealthPreventive Dentistry

Oral Cancer and the Race Against Time: Use of Psoriasin (S100A7) as a Predictive Marker to Enhance Assessment of Cancer Risk in Oral Lesions

by V. Thorburn, BMSc, MSc, DDS Candidate; C.S. Dong, DMD, BSc (Dent), MSc (Prosthodontics), FRCD(C) and M.R. Darling, BChD, MSc (Dent), MSc (Med), MChD

Introduction Oral squamous cell carcinoma (OSCC) is a potentially debilitating and deadly disease, particularly when diagnosed at an advanced stage.1 Early detection drastically improves prognostic outcomes, making diagnosis a race against time.2 Most cases of OSCC begin as a precursor

May 7, 2019 News News

Dentists Could Play a Key Role in Identifying Domestic Violence Cases: Study

by CTV News

Patients visiting the dentist for lesions to the jaw and teeth could be victims of domestic violence, U.S. researchers warn. Oral biomarkers that might signal domestic violence include tears, fractures, breaks, and chips in the teeth and mouth. Published in

December 11, 2018 Feature Oral HealthProactive Intervention Dentistry

Psoriasin: A New Biomarker in the Identification of Cancer Risk in Oral Lesions

by M.R. Darling, BChd, MSc (Dent), MSc (Med), MChD; A. Hassan, BMedSci (Hons Pathology) Candidate; L. McLean, DDS. Oral and Maxillofacial Surgery Resident

Introduction Approximately 90% or more of oral cancers are squamous cell carcinomas (OSCCs). These often begin as potentially malignant oral lesions such as a white patch (leukoplakia; Fig. 1), or red patch (erythroplakia; Fig. 2), 1 which progress to an